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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name ROCK-1 siRNA
ncRNA Category siRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79
Methods siRNA transfection, qRT-PCR, Western blot
Expression pattern associated
Functional description Adhesive ability of Y79 cells was enhanced following ROCK-1 siRNA treatment. Invasiveness of Y79 cells also decreased in Y79 cells transfected with ROCK-1 siRNA.
PubMed ID 24528629
Year 2014
Title The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells.
Drug-related ncRNA NO

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